Improved microcirculatory effect of D-allose on hepatic ischemia reperfusion following partial hepatectomy in cirrhotic rat liver

被引:40
作者
Hossain, Mohammad Akram
Wakabayashi, Hisao
Izuishi, Kunihiko
Okano, Keiichi
Yachida, Shinichi
Tokuda, Masaaki
Izumori, Ken
Maeta, Hajime
机构
[1] Kagawa Ind Support Fdn, Takamatsu, Kagawa 7610301, Japan
[2] Kagawa Univ, Dept Surg 1, Fac Med, Miki, Kagawa 7610793, Japan
[3] Kagawa Univ, Dept Cell Physiol, Fac Med, Miki, Kagawa 7610793, Japan
[4] Kagawa Univ, Dept Biochem & Food Sci, Fac Agr, Miki, Kagawa 7610795, Japan
关键词
D-allose; liver cirrhosis; ischemia/reperfusion; hemodynamics;
D O I
10.1263/jbb.101.369
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
D-Allose, one of the rare sugars produced from D-psicose, has been shown to be effective against reperfusion injury after ischemia and partial hepatectomy in cirrhotic rat liver by improving remnant liver blood flow and survival rates, and decreasing liver enzyme levels and liver tissue injury levels. These findings demand further study of the clinical implications of this sugar in view to the advancing fields of liver surgery and tran;plantation.
引用
收藏
页码:369 / 371
页数:3
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