Signal transduction from the B cell antigen-receptor
被引:177
作者:
Campbell, KS
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机构:
Fox Chase Canc Ctr, Inst Canc Res, Div Basic Sci, Philadelphia, PA 19111 USAFox Chase Canc Ctr, Inst Canc Res, Div Basic Sci, Philadelphia, PA 19111 USA
Campbell, KS
[1
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机构:
[1] Fox Chase Canc Ctr, Inst Canc Res, Div Basic Sci, Philadelphia, PA 19111 USA
Ligation of the B cell antigen-receptor triggers an intricate maze of intercalated biochemical events that ultimately affect B cell biological responses; Recent advances have helped to connect many loose ends by identifying key adaptor proteins, such as BLNK/SLP-65, defining crucial roles for phosphatidylinositol-3-kinase and mapping pathways controlling the mitogen-activated protein kinases (ERK, JNK and p38).