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Phonological processing in dyslexic children: a study combining functional imaging and event related potentials

被引：87
作者：
Georgiewa, P
Rzanny, R
Gaser, C
Gerhard, UJ
Vieweg, U
Freesmeyer, D
Mentzel, HJ
Kaiser, WA
Blanz, B
机构：
[1] Univ Jena, Dept Child & Adolescent Psychiat, D-07740 Jena, Germany
[2] Univ Jena, Inst Diagnost & Intervent Radiol, D-07740 Jena, Germany
[3] Univ Jena, Dept Psychiat, D-07740 Jena, Germany
来源：
NEUROSCIENCE LETTERS | 2002年 / 318卷 / 01期
关键词：
developmental dyslexia; phonological processing; children; functional magnetic resonance imaging; event related potential; Broca's area; reading; P3;
D O I：
10.1016/S0304-3940(01)02236-4
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Difficulties in phonological processing are currently considered one of the major causes for dyslexia. Nine dyslexic children and eight control children were investigated using functional magnetic resonance imaging (fMRI) during non-oral reading of German words. All subjects silently read words and pronounceable non-words in an event related potentials (ERP) investigation, as well. The fMRI showed a significant difference in the activation in the left inferior frontal gyrus between the dyslexic and control groups, resulting from a hyperactivation in the dyslexics. The ERP scalp distribution showed a significant distinction between the two groups concerning the topographic difference for left frontal electrodes in a time window 250-600 ms after stimulus onset for non-word reading. Both the fMRI and the ERP results support differences in phonological processing between dyslexic and normal-reading children. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
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页码：5 / 8
页数：4
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