Linkage map integration

被引：41

作者：

Collins, A ^{[1
]}

Teague, J ^{[1
]}

Keats, BJ ^{[1
]}

Morton, NE ^{[1
]}

机构：

[1] LOUISIANA STATE UNIV CTR,DEPT BIOMETRY & GENET,NEW ORLEANS,LA 70112

来源：

GENOMICS | 1996年 / 36卷 / 01期

关键词：

D O I：

10.1006/geno.1996.0436

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The algorithms that drive the map+ program for locus-oriented linkage mapping are presented. They depend on the enhanced location database program ldb+ to specify an initial comprehensive map that includes all loci in the summary lod file. Subsequently the map may be edited or order constrained and is automatically improved by estimating the location of each locus conditional on the remainder, beginning with the most discrepant loci. Operating characteristics permit rapid and accurate construction of linkage maps with several hundred loci. The map+ program also performs nondisjunction mapping with tests of nonstandard recombination. We have released map+ on Internet as a source program in the C language together with the location database that now includes the LODSOURCE database. The anonymous ftp is cedar.genetics.soton.ac.uk and the World Wide Web address is http://cedar.genetics.soton.ac.uk/public html. (C) 1996 Academic Press, Inc.

引用

页码：157 / 162

页数：6

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