Characterization of the plasmidic beta-lactamase CMY-2, which is responsible for cephamycin resistance

被引：151

作者：

Bauernfeind, A ^{[1
]}

Stemplinger, I ^{[1
]}

Jungwirth, R ^{[1
]}

Giamarellou, H ^{[1
]}

机构：

[1] LAIKON GEN HOSP,ATHENS,GREECE

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1996年 / 40卷 / 01期

关键词：

D O I：

10.1128/AAC.40.1.221

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The phenotype of Klebsiella pneumoniae HEL-1 indicates a plasmidic cephamycinase gene (bla(CMY-2)). Its sequence shows one open reading frame coding for a protein of 381 amino acids. CMY-2 is classified as class C beta-lactamase that is closely related to the plasmidic enzymes BIL-1 and LAT-1 and the chromosomal AmpC of Citrobacter freundii. The bla(CMY-2) gene possibly was translocated onto a plasmid of C. freundii which spread to K. pneumoniae.

引用

页码：221 / 224

页数：4

共 25 条

[1] THE STRUCTURE OF BETA-LACTAMASES [J].