PD-1 blockade: rescue from a near-death experience

被引：23

作者：

Blattman, JN ^{[1
]}

Greenberg, PD

机构：

[1] Univ Washington, Dept Immunol, Seattle, WA 98195 USA

[2] Fred Hutchinson Canc Res Ctr, Program Immunol, Seattle, WA 98109 USA

来源：

NATURE IMMUNOLOGY | 2006年 / 7卷 / 03期

关键词：

D O I：

10.1038/ni0306-227

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

It is unclear whether T cell exhaustion is reversible. A recent Nature paper shows that in vivo blockade of the inhibitory molecule PD-1 can restore the function of exhausted CD8+ T cells during chronic viral infection. © 2006 Nature Publishing Group.

引用

页码：227 / 228

页数：2

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