The enigmatic relationship between mitochondrial dysfunction and Leber's hereditary optic neuropathy

被引:61
作者
Brown, MD [1 ]
机构
[1] Emory Univ, Sch Med, Ctr Mol Med, Atlanta, GA 30322 USA
关键词
D O I
10.1016/S0022-510X(99)00087-8
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:1 / 5
页数:5
相关论文
共 26 条
[1]  
BROWN MD, 1994, CLIN NEUROSCI, V2, P138
[2]  
Brown MD, 1997, AM J HUM GENET, V60, P381
[3]   PHYLOGENETIC ANALYSIS OF LEBERS HEREDITARY OPTIC NEUROPATHY MITOCHONDRIAL DNAS INDICATES MULTIPLE INDEPENDENT OCCURRENCES OF THE COMMON MUTATIONS [J].
BROWN, MD ;
TORRONI, A ;
RECKORD, CL ;
WALLACE, DC .
HUMAN MUTATION, 1995, 6 (04) :311-325
[4]  
BROWN MD, 1999, UNPUB OXIDATIVE PHOS
[5]   Leber's hereditary optic neuropathy: Biochemical effect of 11778/ND4 and 3460/ND1 mutations and correlation with the mitochondrial genotype [J].
Carelli, V ;
Ghelli, A ;
Ratta, M ;
Bacchilega, E ;
Sangiorgi, S ;
Mancini, R ;
Leuzzi, V ;
Cortelli, P ;
Montagna, P ;
Lugaresi, E ;
Esposti, MD .
NEUROLOGY, 1997, 48 (06) :1623-1632
[6]   Functional consequences of the 3460-bp mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy [J].
Cock, HR ;
Cooper, JM ;
Schapira, AHV .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 1999, 165 (01) :10-17
[7]  
COCK HR, 1995, AM J HUM GENET, V57, P1501
[8]   The influence of nuclear background on the biochemical expression of 3460 Leber's hereditary optic neuropathy [J].
Cock, HR ;
Tabrizi, SJ ;
Cooper, JM ;
Schapira, AHV .
ANNALS OF NEUROLOGY, 1998, 44 (02) :187-193
[9]   FUNCTIONAL ALTERATIONS OF THE MITOCHONDRIALLY ENCODED ND4 SUBUNIT ASSOCIATED WITH LEBERS HEREDITARY OPTIC NEUROPATHY [J].
ESPOSTI, MD ;
CARELLI, V ;
GHELLI, A ;
RATTA, M ;
CRIMI, M ;
SANGIORGI, S ;
MONTAGNA, P ;
LENAZ, G ;
LUGARESI, E ;
CORTELLI, P .
FEBS LETTERS, 1994, 352 (03) :375-379
[10]   Respiration and growth defects in transmitochondrial cell lines carrying the 11778 mutation associated with Leber's hereditary optic neuropathy [J].
Hofhaus, G ;
Johns, DR ;
Hurko, O ;
Attardi, G ;
Chomyn, A .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (22) :13155-13161