Venous thrombosis in an ALS population over four years

被引：25

作者：

Elman, LB

Siderowf, A

Houseman, G

Kelley, M

Mccluskey, LF

机构：

[1] Univ Penn, Penn Neurol Inst, Philadelphia, PA 19107 USA

[2] ALS Assoc, Greater Philadelphia Cha, PA USA

来源：

AMYOTROPHIC LATERAL SCLEROSIS | 2005年 / 6卷 / 04期

关键词：

amyotrophic lateral sclerosis; venous thromboembolism; deep venous thrombosis; pulmonary embolism;

D O I：

10.1080/14660820510043226

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We conducted a retrospective chart review of all ALS patients seen at our institution over four years to determine the incidence of venous thromboembolism and to identify risk factors in this population. Events occurred in 13 of 438 patients (2.97%), yielding an annual incidence rate of 33.1 events per 1000 patients (95% CI 17.5 - 55.3). ALS patients have a risk of venous thromboembolism that is higher than the general population but lower than the population of patients with acute stroke or spinal cord injury. Immobility was significantly associated with increased risk of venous thrombosis (RR = 4.96; 95% CI 1.39 - 17.78).

引用

收藏

页码：246 / 249

页数：4

相关论文

共 10 条

[1] THE CLINICAL COURSE OF PULMONARY-EMBOLISM [J].

CARSON, JL ;

KELLEY, MA ;

DUFF, A ;

WEG, JG ;

FULKERSON, WJ ;

PALEVSKY, HI ;

SCHWARTZ, JS ;

THOMPSON, BT ;

POPOVICH, J ;

HOBBINS, TE ;

SPERA, MA ;

ALAVI, A ;

TERRIN, ML .

NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (19) :1240-1245

[2]

HORLANDER KT, 1992, ARCH INTERN MED, V163, P1711

[3] Pneumatic sequential compression reduces the risk of deep vein thrombosis in stroke patients [J].

Kamran, SI ;

Downey, D ;

Ruff, RL .

NEUROLOGY, 1998, 50 (06) :1683-1688

[4] ARE PATIENTS WITH MULTIPLE-SCLEROSIS PROTECTED FROM THROMBOPHLEBITIS AND PULMONARY-EMBOLISM [J].

KAUFMAN, J ;

KHATRI, BO ;

RIENDL, P .

CHEST, 1988, 94 (05) :998-1001

[5] THE EPIDEMIOLOGY OF DIAGNOSED PULMONARY-EMBOLISM AND DEEP VENOUS THROMBOSIS IN THE ELDERLY [J].

KNIFFIN, WD ;

BARON, JA ;

BARRETT, J ;

BIRKMEYER, JD ;

ANDERSON, FA .

ARCHIVES OF INTERNAL MEDICINE, 1994, 154 (08) :861-866

[6]

Lamb G C, 1993, J Am Paraplegia Soc, V16, P153

[7] DEEP VENOUS THROMBOSIS AND PULMONARY-EMBOLISM IN PATIENTS WITH ACUTE SPINAL-CORD INJURY - A COMPARISON WITH NONPARALYZED PATIENTS IMMOBILIZED DUE TO SPINAL FRACTURES [J].

MYLLYNEN, P ;

KAMMONEN, M ;

ROKKANEN, P ;

BOSTMAN, O ;

LALLA, M ;

LAASONEN, E .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1985, 25 (06) :541-543

[8]

Virchow R., 1856, GESAMMELTE ABHANDLUN

[9] DEEP VENOUS THROMBOSIS OF LEGS AFTER STROKES .1. INCIDENCE AND PREDISPOSING FACTORS [J].

WARLOW, C ;

OGSTON, D ;

DOUGLAS, AS .

BRITISH MEDICAL JOURNAL, 1976, 1 (6019) :1178-1181

[10] DEEP VENOUS THROMBOSIS IN SPINAL-CORD INJURY - OVERVIEW OF THE PROBLEM [J].

WEINGARDEN, SI .

CHEST, 1992, 102 (06) :S636-S639