Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy

被引:84
作者
Shepherd, FA [1 ]
Tsao, MS
机构
[1] Princess Margaret Hosp, Toronto, ON M4X 1K9, Canada
[2] Univ Toronto, Toronto, ON, Canada
关键词
D O I
10.1200/JCO.2005.04.4420
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1219 / 1220
页数:2
相关论文
共 8 条
[1]   Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib [J].
Eberhard, DA ;
Johnson, BE ;
Amler, LC ;
Goddard, AD ;
Heldens, SL ;
Herbst, RS ;
Ince, WL ;
Jänne, PA ;
Januario, T ;
Johnson, DH ;
Klein, P ;
Miller, VA ;
Ostland, MA ;
Ramies, DA ;
Sebisanovic, D ;
Stinson, JA ;
Zhang, YR ;
Seshagiri, S ;
Hillan, KJ .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (25) :5900-5909
[2]  
Gumerlock PH, 2005, J CLIN ONCOL, V23, p623S
[3]   Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: A Southwest Oncology Group Study [J].
Hirsch, FR ;
Varella-Garcia, M ;
McCoy, J ;
West, H ;
Xavier, AC ;
Gumerlock, P ;
Bunn, PA ;
Franklin, WA ;
Crowley, J ;
Gandara, DR .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (28) :6838-6845
[4]   Selecting patients for epidermal growth factor receptor inhibitor treatment:: A FISH story or a tale of mutations? [J].
Johnson, BE ;
Jänne, PAJ .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (28) :6813-6816
[5]   EGFR and ErbB2 mutation status in Japanese lung cancer patients [J].
Sasaki, H ;
Shimizu, S ;
Endo, K ;
Takada, M ;
Kawahara, M ;
Tanaka, H ;
Matsumura, A ;
Iuchi, K ;
Haneda, H ;
Suzuki, E ;
Kobayashi, Y ;
Yano, M ;
Fujii, Y .
INTERNATIONAL JOURNAL OF CANCER, 2006, 118 (01) :180-184
[6]   Erlotinib in previously treated non-small-cell lung cancer [J].
Shepherd, FA ;
Pereira, JR ;
Ciuleanu, T ;
Tan, EH ;
Hirsh, V ;
Thongprasert, S ;
Campos, D ;
Maoleekoonpiroj, S ;
Smylie, M ;
Martins, R ;
van Kooten, M ;
Dediu, M ;
Findlay, B ;
Tu, DS ;
Johnston, D ;
Bezjak, A ;
Clark, G ;
Santabárbara, P ;
Seymour, L .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (02) :123-132
[7]   Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer [J].
Takano, T ;
Ohe, Y ;
Sakamoto, H ;
Tsuta, K ;
Matsuno, Y ;
Tateishi, U ;
Yamamoto, S ;
Nokihara, H ;
Yamamoto, N ;
Sekine, I ;
Kunitoh, H ;
Shibata, T ;
Sakiyama, T ;
Yoshida, T ;
Tamura, T .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (28) :6829-6837
[8]   Erlotinib in lung cancer - Molecular and clinical predictors of outcome [J].
Tsao, MS ;
Sakurada, A ;
Cutz, JC ;
Zhu, CQ ;
Kamel-Reid, S ;
Squire, J ;
Lorimer, I ;
Zhang, T ;
Liu, N ;
Daneshmand, M ;
Marrano, P ;
Santos, GD ;
Lagarde, A ;
Richardson, F ;
Seymour, L ;
Whitehead, M ;
Ding, KY ;
Pater, J ;
Shepherd, FA .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (02) :133-144