Determinants of persistent detection of human papillomavirus DNA in the uterine cervix

被引：48

作者：

Brisson, J ^{[1
]}

Bairati, I ^{[1
]}

Morin, C ^{[1
]}

Fortier, M ^{[1
]}

Bouchard, C ^{[1
]}

Christen, A ^{[1
]}

Bernard, P ^{[1
]}

Roy, M ^{[1
]}

Meisels, A ^{[1
]}

机构：

[1] UNIV LAVAL, EPIDEMIOL RES UNIT, DEPT OBSTET & GYNECOL, QUEBEC CITY, PQ G1K 7P4, CANADA

来源：

JOURNAL OF INFECTIOUS DISEASES | 1996年 / 173卷 / 04期

关键词：

D O I：

10.1093/infdis/173.4.794

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To identify factors associated with persistence of human papillomavirus (HPV) DNA in the uterine cervix, 179 women who were 18-49 years old and who had normal cytologies and positive cervical HPV DNA tests at a routine periodic examination were analyzed. Among them, 91 (50.8%) remained HPV-positive a few months (mean, 11 weeks) later. Persistence was higher in women who had used oral contraceptives for greater than or equal to 2 years (odds ratio, 3.9; 95% confidence interval, 1.5-10.3) compared with those who never used oral contraceptives or used them for <2 years, HPV types 16, 18, and 31/33/35 appeared more persistent (odds ratio, 2.5; 95% confidence interval, 1.0-6.2) than other types. Persistence seemed to increase with virus load and decrease with increasing interval between examinations.

引用

页码：794 / 799

页数：6

共 39 条

[1] GENITAL HUMAN PAPILLOMAVIRUS INFECTION IN FEMALE UNIVERSITY-STUDENTS AS DETERMINED BY A PCR-BASED METHOD [J].

BAUER, HM ;

TING, Y ;

GREER, CE ;

CHAMBERS, JC ;

TASHIRO, CJ ;

CHIMERA, J ;

REINGOLD, A ;

MANOS, MM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1991, 265 (04) :472-477

[2]

BOSCH FX, 1993, CANCER EPIDEM BIOMAR, V2, P415

[3] RISK-FACTORS FOR CERVICAL INTRAEPITHELIAL NEOPLASIA - DIFFERENCES BETWEEN LOW-GRADE AND HIGH-GRADE LESIONS [J].

BRISSON, J ;

MORIN, C ;

FORTIER, M ;

ROY, M ;

BOUCHARD, C ;

LECLERC, J ;

CHRISTEN, A ;

GUIMONT, C ;

PENAULT, F ;

MEISELS, A .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 1994, 140 (08) :700-710

[4] THE BETHESDA SYSTEM FOR REPORTING CERVICAL VAGINAL CYTOLOGIC DIAGNOSES - REPORT OF THE 1991 BETHESDA WORKSHOP [J].

BRODER, S .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1992, 267 (14) :1892-1892

[5] PROGESTERONE AND GLUCOCORTICOID RESPONSE ELEMENTS OCCUR IN THE LONG CONTROL REGIONS OF SEVERAL HUMAN PAPILLOMAVIRUSES INVOLVED IN ANOGENITAL NEOPLASIA [J].

CHAN, WK ;

KLOCK, G ;

BERNARD, HU .

JOURNAL OF VIROLOGY, 1989, 63 (08) :3261-3269

[6] DETECTION OF HUMAN PAPILLOMAVIRUS DEOXYRIBONUCLEIC-ACID BY FILTER INSITU HYBRIDIZATION DURING PREGNANCY [J].

CZEGLEDY, J ;

GERGELY, L ;

ENDRODI, I .

JOURNAL OF MEDICAL VIROLOGY, 1989, 28 (04) :250-254

[7]

DEVILLIERS EM, 1987, LANCET, V2, P703

[8] HUMAN PAPILLOMAVIRUS DNA IN WOMEN WITHOUT AND WITH CYTOLOGICAL ABNORMALITIES - RESULTS OF A 5-YEAR FOLLOW-UP-STUDY [J].

DEVILLIERS, EM ;

WAGNER, D ;

SCHNEIDER, A ;

WESCH, H ;

MUNZ, F ;

MIKLAW, H ;

HAUSEN, HZ .

GYNECOLOGIC ONCOLOGY, 1992, 44 (01) :33-39

[9] SYMPTOMATIC AND ASYMPTOMATIC CERVICAL INFECTIONS WITH HUMAN PAPILLOMAVIRUS DURING PREGNANCY [J].

FIFE, KH ;

ROGERS, RE ;

ZWICKL, BW .

JOURNAL OF INFECTIOUS DISEASES, 1987, 156 (06) :904-911

[10] THE UPSTREAM REGULATORY REGION OF THE HUMAN PAPILLOMA VIRUS-16 CONTAINS AN E2-PROTEIN-INDEPENDENT ENHANCER WHICH IS SPECIFIC FOR CERVICAL-CARCINOMA CELLS AND REGULATED BY GLUCOCORTICOID HORMONES [J].

GLOSS, B ;

BERNARD, HU ;

SEEDORF, K ;

KLOCK, G .

EMBO JOURNAL, 1987, 6 (12) :3735-3743

← 1 2 3 4 →