Implementation of an automatic alarms system for early detection of patients with severe sepsis

被引:11
作者
Maria Ferreras, Jose [1 ]
Judez, Diego [2 ]
Tirado, Gabriel [3 ]
Aspiroz, Carmen [4 ]
Martinez-Alvarez, Rosa [5 ]
Dorado, Paloma [3 ]
Ezpeleta, Ana [3 ]
Marron, Rafael [6 ]
Gargallo, Begona [1 ]
Herranz, Clara [1 ]
机构
[1] Hosp Royo Villanova, Serv Urgencias, Zaragoza, Spain
[2] Hosp Alcaniz, Serv Anestesia, Teruel, Spain
[3] Hosp Royo Villanova, Serv Cuidados Intens, Zaragoza, Spain
[4] Hosp Royo Villanova, Microbiol Serv, Zaragoza, Spain
[5] Hosp Royo Villanova, Med Interna Serv, Zaragoza, Spain
[6] Hosp Miguel Servet, Serv Urgencias, Zaragoza, Spain
来源
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA | 2015年 / 33卷 / 08期
关键词
Sepsis; Emergencies; Outcome assessment; TRENDS; CARE; EPIDEMIOLOGY; OUTCOMES;
D O I
10.1016/j.eimc.2015.01.002
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Objective: The objective of this study was to assess the usefulness of a software tool integrated into the medical electronic history at the time of emergency triage. The aim was the early detection of patients with severe sepsis, and the potential impact of this software tool on reducing the mortality rate in patients treated. Method: The study consisted of two comparative samples. Patient selection was performed retrospectively into two groups using ICD-9 codes from the hospital and emergency department discharge reports. The codes were 038.9, 995.9 and 995.92 for sepsis, and 785.52 for severe sepsis and septic shock. The sample called alarms consisted of patients studied after implementing the sepsis alarm system in the Emergency Department computer system. There were two types of alarms, a serious one and an alert one depending on the on vital signs defined. The historical sample called no alarms consisted of patients seen in the Emergency Department during the year before the introduction of the alarm system. Results: The compliance rate of the sepsis treatment package was higher in the alarms sample, compared to the sample without alarms, with blood cultures, 96.3% versus 80.9% (P < .001), antibiotic treatment in less than one hour, 62.9% vs. 39.3% (P < .001), determination of lactic acid, 91.4% vs. 77.9% (P < .001), and applying appropriate volume, 57.7% vs 54.3% (P = .052), respectively. The hospital mortality was reduced in absolute terms from 25% in the sample without alarms to 13.6% in the sample with alarms. Survival at 30 days was higher in the sample with alarms (Log Rank = .004). Conclusions: There were no studies that evaluated the effectiveness of an alarm system in our literature search. An electronic identification system for patients with sepsis allows acting earlier, better compliance with basic measures, and a reduction in hospital stay and mortality. (C) 2015 Elsevier Espana, S.L.U. and Sociedad Espanola de Enfermedades Infecciosas y Microbiologia Clinica. All rights reserved.
引用
收藏
页码:508 / 515
页数:8
相关论文
共 18 条
[1]  
Tejedo AA, 2009, EMERGENCIAS, V21, P255
[2]  
[Anonymous], COSTES MEDIOS SANITA
[3]   Temporal Trends in the Epidemiology of Severe Postoperative Sepsis after Elective Surgery A Large, Nationwide Sample [J].
Bateman, Brian T. ;
Schmidt, Ulrich ;
Berman, Mitchell F. ;
Bittner, Edward A. .
ANESTHESIOLOGY, 2010, 112 (04) :917-925
[4]   Promoting Global Research Excellence in Severe Sepsis (PROGRESS): Lessons from an International Sepsis Registry [J].
Beale, R. ;
Reinhart, K. ;
Brunkhorst, F. M. ;
Dobb, G. ;
Levy, M. ;
Martin, G. ;
Martin, C. ;
Ramsey, G. ;
Silva, E. ;
Vallet, B. ;
Vincent, J. -L. ;
Janes, J. M. ;
Sarwat, S. ;
Williams, M. D. .
INFECTION, 2009, 37 (03) :222-232
[5]   Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012 [J].
Dellinger, R. Phillip ;
Levy, Mitchell M. ;
Rhodes, Andrew ;
Annane, Djillali ;
Gerlach, Herwig ;
Opal, Steven M. ;
Sevransky, Jonathan E. ;
Sprung, Charles L. ;
Douglas, Ivor S. ;
Jaeschke, Roman ;
Osborn, Tiffany M. ;
Nunnally, Mark E. ;
Townsend, Sean R. ;
Reinhart, Konrad ;
Kleinpell, Ruth M. ;
Angus, Derek C. ;
Deutschman, Clifford S. ;
Machado, Flavia R. ;
Rubenfeld, Gordon D. ;
Webb, Steven A. ;
Beale, Richard J. ;
Vincent, Jean-Louis ;
Moreno, Rui ;
Aitken, Leanne ;
Al Rahma, Hussain ;
Annane, Dijillali ;
Bernard, Gordon R. ;
Biban, Paolo ;
Bion, Julian F. ;
Calandra, Thierry ;
Carcillo, Joseph A. ;
Clemmer, Terry P. ;
Divatia, J. V. ;
Du, Bin ;
Fujishima, Seitaro ;
Gando, Satoshi ;
Goodyear-Bruch, Caryl ;
Guyatt, Gordon ;
Hazelzet, Jan A. ;
Hirasawa, Hiroyuki ;
Hollenberg, Steven M. ;
Jacobi, Judith ;
Jenkins, Ian ;
Jimenez, Edgar ;
Jones, Alan E. ;
Kacmarek, Robert M. ;
Kern, Winfried ;
Koh, Shin Ok ;
Kotani, Joji ;
Levy, Mitchell .
CRITICAL CARE MEDICINE, 2013, 41 (02) :580-637
[6]   Sepsis incidence and outcome:: Contrasting the intensive care unit with the hospital ward [J].
Esteban, Andres ;
Frutos-Vivar, Fernando ;
Ferguson, Niall D. ;
Penuelas, Oscar ;
Lorente, Jose Angel ;
Gordo, Federico ;
Honrubia, Teresa ;
Algora, Alejandro ;
Bustos, Alejandra ;
Garcia, Gema ;
Rodriguez Diaz-Reganon, Inmaculada ;
Ruiz de Luna, Rafael .
CRITICAL CARE MEDICINE, 2007, 35 (05) :1284-1289
[7]   Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain [J].
Ferrer, Ricard ;
Artigas, Antonio ;
Levy, Mitchell M. ;
Blanco, Jesus ;
Gonzalez-Diaz, Gumersindo ;
Garnacho-Montero, Jose ;
Ibanez, Jordi ;
Palencia, Eduardo ;
Quintana, Manuel ;
de la Torre-Prados, Maria Victoria .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 299 (19) :2294-2303
[8]   The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study [J].
Gao, F ;
Melody, T ;
Daniels, DF ;
Giles, S ;
Fox, S .
CRITICAL CARE, 2005, 9 (06) :R764-R770
[9]   Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock [J].
Kumar, Arland ;
Roberts, Daniel ;
Wood, Kenneth E. ;
Light, Bruce ;
Parrillo, Joseph E. ;
Sharma, Satendra ;
Suppes, Robert ;
Feinstein, Daniel ;
Zanotti, Sergio ;
Taiberg, Leo ;
Gurka, David ;
Kumar, Aseem ;
Cheang, Mary .
CRITICAL CARE MEDICINE, 2006, 34 (06) :1589-1596
[10]   Nationwide Trends of Severe Sepsis in the 21st Century (2000-2007) [J].
Kumar, Gagan ;
Kumar, Nilay ;
Taneja, Amit ;
Kaleekal, Thomas ;
Tarima, Sergey ;
McGinley, Emily ;
Jimenez, Edgar ;
Mohan, Anand ;
Khan, Rumi Ahmed ;
Whittle, Jeff ;
Jacobs, Elizabeth ;
Nanchal, Rahul .
CHEST, 2011, 140 (05) :1223-1231