Geometric parameters in nucleic acids: Nitrogenous bases

被引：163

作者：

Clowney, L ^{[1
]}

Jain, SC ^{[1
]}

Srinivasan, AR ^{[1
]}

Westbrook, J ^{[1
]}

Olson, WK ^{[1
]}

Berman, HM ^{[1
]}

机构：

[1] RUTGERS STATE UNIV,DEPT CHEM,PISCATAWAY,NJ 08855

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 118卷 / 03期

关键词：

D O I：

10.1021/ja952883d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present estimates of the bond-length and bond-angle parameters for the nitrogenous base side groups of nucleic acids. These values are the result of a statistical survey of small molecules in the Cambridge Structural Database for which high-resolution X-ray and neutron crystal structures are available. The statistics include arithmetic means and standard deviations for the different samples, as well as comparisons of the population distributions for sugar- and non-sugar-derivatized bases. These accumulated data provide appropriate target values for refinements of oligonucleotide structures, as well as sets of standard atomic coordinates for the five common bases.

引用

页码：509 / 518

页数：10

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