Are we prescribing multiple courses of antenatal corticosteroids? A survey of practice in the UK

被引:103
作者
Brocklehurst, P [1 ]
Gates, S
McKenzie-McHarg, K
Alfirevic, Z
Chamberlain, G
机构
[1] Radcliffe Infirm, Natl Perinatal Epidemiol Unit, Oxford OX2 6HE, England
[2] Liverpool Womens Hosp, Liverpool, Merseyside, England
[3] Singleton Hosp, Swansea SA2 8QA, W Glam, Wales
来源
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1999年 / 106卷 / 09期
关键词
D O I
10.1111/j.1471-0528.1999.tb08440.x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A postal questionnaire concerned with prescribing antenatal corticosteroids was sent to one named clinician at each of 279 obstetric units in the UK. They were asked whether their unit prescribed repeated courses, the indications for which these would be prescribed, the interval between courses, the drugs and regimens used and whether they would be willing to participate in a proposed randomised controlled trial. The response rate was 75%. Of the respondents, 98% prescribed repeated courses; the indications most commonly cited by units who prescribed steroids were prelabour spontaneous rupture of membranes (84.2%) and suspected preterm labour (81.8%). 70.6% of units were willing to participate in the proposed trial.
引用
收藏
页码:977 / 979
页数:3
相关论文
共 6 条
[1]  
CROWLEY P, 1998, COCHRANE DATABASE SY
[2]  
Dunlop S A, 1997, J Matern Fetal Med, V6, P309
[3]   Repeated use of betamethasone in rabbits: Effects of treatment variation on adrenal suppression, pulmonary maturation, and pregnancy outcome [J].
Pratt, L ;
Magness, RR ;
Phernetton, T ;
Hendricks, SK ;
Abbott, DH ;
Bird, IM .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1999, 180 (04) :995-1005
[4]   Use of corticosteroids by Australian obstetricians - A survey of clinical practice [J].
Quinlivan, JA ;
Evans, SF ;
Dunlop, SA ;
Beazley, LD ;
Newnham, JP .
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 1998, 38 (01) :1-7
[5]   Impact of multiple antenatal doses of betamethasone on growth and development of mice offspring [J].
Stewart, JD ;
Gonzalez, CL ;
Christensen, HD ;
Rayburn, WF .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1997, 177 (05) :1138-1144
[6]   BRAIN-DAMAGE INDUCED BY PRENATAL EXPOSURE TO DEXAMETHASONE IN FETAL RHESUS MACAQUES .1. HIPPOCAMPUS [J].
UNO, H ;
LOHMILLER, L ;
THIEME, C ;
KEMNITZ, JW ;
ENGLE, MJ ;
ROECKER, EB ;
FARRELL, PM .
DEVELOPMENTAL BRAIN RESEARCH, 1990, 53 (02) :157-167