A look at linkage disequilibrium

被引：50

作者：

Boehnke, M ^{[1
]}

机构：

[1] Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA

来源：

NATURE GENETICS | 2000年 / 25卷 / 03期

关键词：

D O I：

10.1038/76980

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The extent of linkage disequilibrium critically determines the efficiency of strategies to identify genetic variants that predispose to human disease. New data indicate that the extent of disequilibrium is highly variable across the genome, and that differences in disequilibrium levels between isolated and mixed populations are modest.

引用

页码：246 / 247

页数：2

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