A plant miRNA contributes to antibacterial resistance by repressing auxin signaling

被引：1397

作者：

Navarro, L

Dunoyer, P

Jay, F

Arnold, B

Dharmasiri, N

Estelle, M

Voinnet, O

Jones, JDG

机构：

[1] CNRS, Inst Biol Mol Plantes, F-67084 Strasbourg, France

[2] John Innes Ctr Plant Sci Res, Sainsbury Lab, Norwich NR4 7UH, Norfolk, England

[3] Indiana Univ, Dept Biol, Bloomington, IN 47405 USA

来源：

SCIENCE | 2006年 / 312卷 / 5772期

关键词：

D O I：

10.1126/science.1126088

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Plants and animals activate defenses after perceiving pathogen-associated molecular patterns (PAMPs) such as bacterial flagellin. In Arabidopsis, perception of flagellin increases resistance to the bacterium Pseudomonas syringae, although the molecular mechanisms involved remain elusive. Here, we show that a flagellin-derived peptide induces a plant microRNA (miRNA) that negatively regulates messenger RNAs for the F-box auxin receptors TIR1, AFB2, and AFB3. Repression of auxin signaling restricts P. syringae growth, implicating auxin in disease susceptibility and miRNA-mediated suppression of auxin signaling in resistance.

引用

收藏

页码：436 / 439

页数：4

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