Structure activity relationships of tetrahydrocannabinol analogues on human cannabinoid receptors.

被引：87

作者：

Gareau, Y

Dufresne, C

Gallant, M

Rochette, C

Sawyer, N

Slipetz, DM

Tremblay, N

Weech, PK

Metters, KM

Labelle, M

机构：

[1] Merck Frosst Ctr. Therapeut. Res., Pointe-Claire-Dorval, Que. H9R 4P8

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 02期

关键词：

D O I：

10.1016/0960-894X(95)00573-C

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of Delta(8)-tetrahydrocannabinol (THC) and biphenylic derivatives were prepared and their binding affinity for both human cannabinoid receptors hCB(1) and hCB(2) evaluated.

引用

页码：189 / 194

页数：6

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