Safety of rasagiline in elderly patients with Parkinson disease

被引：41

作者：

Goetz, CG

Schwid, SR

Eberly, SW

Oakes, D

Shoulson, I

机构：

[1] Rush Univ, Med Ctr, Chicago, IL 60612 USA

[2] Univ Rochester, Rochester, NY 14627 USA

来源：

NEUROLOGY | 2006年 / 66卷 / 09期

关键词：

D O I：

10.1212/01.wnl.0000210692.95595.1c

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors examined age effects on adverse events from two randomized, controlled trials of rasagiline, comparing younger (younger than 70 years) and older (70 years and older) subjects. Older patients were more prone to serious adverse effects than younger patients, but there was no statistical interaction between age and rasagiline exposure. This absence of an age-rasagiline interaction suggests that rasagiline does not require special safety precautions for elderly subjects with Parkinson disease.

引用

页码：1427 / 1429

页数：3

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