Killing the messenger: new insights into nonsense-mediated mRNA decay

被引：133

作者：

Byers, PH

机构：

[1] Univ Washington, Dept Pathol, Seattle, WA 98195 USA

[2] Univ Washington, Dept Med, Seattle, WA 98195 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2002年 / 109卷 / 01期

关键词：

D O I：

10.1172/JCI200214841

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：3 / 6

页数：4

共 20 条

[1] EVIDENCE TO IMPLICATE TRANSLATION BY RIBOSOMES IN THE MECHANISM BY WHICH NONSENSE CODONS REDUCE THE NUCLEAR-LEVEL OF HUMAN TRIOSEPHOSPHATE ISOMERASE MESSENGER-RNA [J].

BELGRADER, P ;

CHENG, J ;

MAQUAT, LE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (02) :482-486

[2] Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay [J].

Bhattacharya, A ;

Czaplinski, K ;

Trifillis, P ;

He, F ;

Jacobson, A ;

Peltz, SW .

RNA, 2000, 6 (09) :1226-1235

[3] A coactivator of pre-mRNA splicing [J].

Blencowe, BJ ;

Issner, R ;

Nickerson, JA ;

Sharp, PA .

GENES & DEVELOPMENT, 1998, 12 (07) :996-1009

[4] A splicing-dependent regulatory mechanism that detects translation signals [J].

Carter, MS ;

Li, SL ;

Wilkinson, MF .

EMBO JOURNAL, 1996, 15 (21) :5965-5975

[5] A REGULATORY MECHANISM THAT DETECTS PREMATURE NONSENSE CODONS IN T-CELL RECEPTOR TRANSCRIPTS IN-VIVO IS REVERSED BY PROTEIN-SYNTHESIS INHIBITORS IN-VITRO [J].

CARTER, MS ;

DOSKOW, J ;

MORRIS, P ;

LI, SL ;

NHIM, RP ;

SANDSTEDT, S ;

WILKINSON, MF .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (48) :28995-29003

[6] INTRONS ARE CIS EFFECTORS OF THE NONSENSE-CODON-MEDIATED REDUCTION IN NUCLEAR MESSENGER-RNA ABUNDANCE [J].

CHENG, J ;

BELGRADER, P ;

ZHOU, XB ;

MAQUAT, LE .

MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (09) :6317-6325

[7] Coupled transcription and translation within nuclei of mammalian cells [J].

Iborra, FJ ;

Jackson, DA ;

Cook, PR .

SCIENCE, 2001, 293 (5532) :1139-1142

[8] Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20 [J].

Ishigaki, Y ;

Li, XJ ;

Serin, G ;

Maquat, LE .

CELL, 2001, 106 (05) :607-617

[9] Tracking COL1A1 RNA in osteogenesis imperfecta: Splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain [J].

Johnson, C ;

Primorac, D ;

McKinstry, M ;

McNeil, J ;

Rowe, D ;

Lawrence, JB .

JOURNAL OF CELL BIOLOGY, 2000, 150 (03) :417-431

[10] Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex [J].

Kataoka, N ;

Diem, MD ;

Kim, VN ;

Yong, J ;

Dreyfuss, G .

EMBO JOURNAL, 2001, 20 (22) :6424-6433

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