重组人脑钠肽治疗充血性心力衰竭的效果观察

被引:3
作者
王新
机构
[1] 常州市第二人民医院心内科
关键词
重组人脑钠肽; 充血性心力衰竭;
D O I
暂无
中图分类号
R541.61 [];
学科分类号
1002 ; 100201 ;
摘要
目的:观察重组人脑钠钛(新活素)治疗充血性心力衰竭的效果及其不良反应。方法:观察组15例在常规综合治疗的基础上加用新活素,对照组15例仅给予常规综合治疗,观察治疗前后患者临床症状、体征、心功能改善情况。结果:对照组显效6例,有效4例,总有效率66.7%;观察组显效10例,有效5例,总有效率100%,两组治疗后心功能改善情况差异有统计学意义(P<0.01)。结论:新活素治疗充血性心力衰竭患者心功能改善显著,疗效确切,副作用小。
引用
收藏
页码:659 / 660
页数:2
相关论文
共 8 条
[1]  
The use of recombinant human B-type natriuret-ic peptide(nesiritide)in the management of acute decom-pensated heart failure. Strain WD. International Journal of Clinical Practice . 2004
[2]  
Guidelines for the diagnosis and treatment of chronic heart failure: executive summary. Karl S.John C,Wilson,S,et al. European Heart Journal . 2005
[3]  
Comparison of effects on left ventricular filling pressure of intravenous nesiritide and high-dose nitroglycerin in patients with decompensated heart failure. Elkayam,U,Akhter,MW,Singh,H,Khan,S,Usman,A. The American Journal of Cardiology . 2004
[4]  
Intravenous nesiritide, a natriuretic peptide, in the treatment of decompensated congestive heart failure. Colucci WS,Elkayam U,Horton DP,et al. The New England Journal of Medicine . 2000
[5]  
Safety and effectiveness of dofetilide for conversion ofatrial fibrillation and nesiritide for acute decompensation of heartfailure. GR INES CL. C ircu lation . 2001
[6]  
Brain natriuretic peptide in the management of heart failure: the versatile neurohormone. de,Denus,S,Pharand,C,Williamson,DR. Chest . 2004
[7]  
Intravenous nesiritide vs.nitroglycerin for treatment of decompensated congestive heart failure: A randomized controlled trial. Young JB,Abraham WT,Stevenson LW,et al. The Journal of The American Medical Association . 2002
[8]   脑利钠肽的临床研究进展 [J].
王爱亮 ;
秦晓同 .
南通大学学报(医学版), 2008, (02) :151-153