新型自由基清除剂依达拉奉对急性脑梗死的治疗作用

被引:38
作者
李竞
冯宏业
任力杰
韩漫夫
梁玉宏
陈婷
白润涛
机构
[1] 深圳市第二人民医院神经内科,深圳市第二人民医院神经内科,深圳市第二人民医院神经内科,深圳市第二人民医院神经内科,深圳市第二人民医院神经内科,深圳市第二人民医院神经内科,深圳市第二人民医院神经内科深圳,深圳,深圳,深圳,深圳,深圳,深圳
关键词
依达拉奉; 自由基; 脑水肿; 急性脑梗死;
D O I
10.16016/j.1000-5404.2005.07.032
中图分类号
R743.33 [脑栓塞];
学科分类号
1002 ;
摘要
目的 观察依达拉奉(MCI 186)治疗急性脑梗死的疗效和安全性。方法 83例急性脑梗死病人随机分为治疗组和对照组。对照组按急性脑梗死常规方法治疗,治疗组在常规治疗基础上加用依达拉奉治疗。两组病例于治疗前、治疗后1个月分别进行巴氏指数(BI)及神经功能缺损量表(CSS)评定,并观察脑水肿程度改变及依达拉奉治疗期间的不良反应。结果 两组治疗后1个月CSS和BI评分均有所改善,但治疗组明显优于对照组(P <0 0 1) ,治疗组2周时中重度(等级为2~3 )脑水肿发生率为12 % ,明显低于对照组3 1% (P <0 0 5 )。依达拉奉治疗期间无明显副作用发生。结论 依达拉奉治疗急性脑梗死是安全有效的。
引用
收藏
页码:663 / 665
页数:3
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