复发性缺血性脑卒中的危险因素、严重程度及短期预后分析

被引:63
作者
田婷 [1 ]
关智媛 [2 ]
石正洪 [1 ]
栗静 [1 ]
冯斌 [1 ]
机构
[1] 兰州大学第二医院神经内科临床医学中心
[2] 兰州大学第二临床医学院
关键词
缺血性脑卒中; 复发; 危险因素; 美国国立卫生研究院卒中量表; 预后;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
目的探讨复发性缺血性脑卒中的危险因素,评价其严重程度及短期预后。方法 2014年3月2015年3月,本院复发性缺血性脑卒中患者238例(复发组),性别和年龄匹配的初发缺血性脑卒中患者378例(初发组)。比较两组患者的临床资料并进行非条件Logistic回归分析;对比两组患者入院和出院时美国国立卫生研究院卒中量表(NIHSS)评分及神经功能好转率。结果复发组脑白质疏松(χ2=8.666)、高血压(χ2=8.189)、吸烟(χ2=6.973)、饮酒(χ2=4.722)的发生率高于初发组(P<0.05)。Logistic回归分析显示,脑白质疏松(OR=1.690,95%CI:1.198~2.384,P=0.003)、高血压(OR=1.715,95%CI:1.135~2.592,P=0.010)、吸烟(OR=1.896,95%CI:1.233~2.915,P=0.004)是复发性缺血性脑卒中的独立危险因素。复发组入院及出院NIHSS评分均显著高于初发组(t=-3.645,t=-4.675,P<0.001),神经功能好转率明显低于初发组(t=2.643,P<0.01)。结论高血压、脑白质疏松、吸烟是复发性缺血性脑卒中的独立危险因素,复发性缺血性脑卒中患者较初发者病情严重,短期神经功能恢复慢。
引用
收藏
页码:172 / 177
页数:6
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