内脂素与胰岛素抵抗和糖尿病

被引：2

作者：

丁焕发

荣海钦

机构：

[1] 山东省内分泌与代谢病研究所

[2] 山东省内分泌与代谢病研究所济南

来源：

医学综述 | 2008年 / 12期

关键词：

内脂素; 前B细胞克隆增强因子; 2型糖尿病; 胰岛素抵抗; 妊娠糖尿病;

D O I：

暂无

中图分类号：

R587.1 [糖尿病];

学科分类号：

1002 ; 100201 ;

摘要：

内脂素是一种主要由内脏脂肪细胞分泌的脂肪细胞因子,其cDNA与前B细胞克隆增强因子相同。可结合并激活胰岛素受体,发挥类胰岛素样作用,降低血糖,同时在胰岛素信号转导中发挥作用。可能是联系机体糖脂代谢的重要分子,它的发现可为研究胰岛素抵抗和糖尿病与肥胖和脂代谢提供新的思路和方法。

引用

页码：1876 / 1878

页数：3

共 10 条

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