小胶质细胞激活的分子机制

被引:12
作者
刘锋
朱长庚
机构
[1] 河北医科大学解剖教研室
[2] 华中科技大学同济医学院脑研究室 河北石家庄
[3] 湖北武汉
关键词
小胶质细胞; 形态学; 免疫学; 细胞因子; NF; 脑内; 小神经胶质; 基础医学; 分子机制; 抗原提呈细胞;
D O I
10.16695/j.cnki.1006-2947.2003.02.025
中图分类号
R329 [人体组织学];
学科分类号
100101 ;
摘要
小胶质细胞激活后表现为中枢神经系统的免疫效应细胞 ,是脑内细胞因子的重要来源和作用部位 ,参与损伤、炎症、MS、AD、癫痫反复发作等脑病理发生过程。关于小胶质细胞激活的机制 ,尤其是其活化过程中信号转导的分子基础 ,是当今小胶质细胞研究的热点。本文对小胶质细胞激活的形态学表现、免疫学特性及其激活的分子机制进行了综述
引用
收藏
页码:177 / 180
页数:4
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