磁敏感加权成像对急性脑梗死缺血半暗带的预测价值

被引:18
作者
梅文丽
刘慧勤
张杰文
陈祖芝
马明明
黄月
机构
[1] 郑州大学人民医院河南省人民医院神经内科
关键词
急性脑梗死; 磁敏感加权成像; 多发低密度血管影; 缺血半暗带;
D O I
10.13507/j.issn.1674-3474.2017.01.018
中图分类号
R445.2 [核磁共振成像]; R743.33 [脑栓塞];
学科分类号
100207 ; 1002 ;
摘要
目的探讨急性脑梗死患者磁敏感加权成像(susceptibility weighted imaging,SWI)多发低密度血管影(multiple hypointensity vessels,MHV)在预测缺血半暗带中的临床应用价值。方法急性脑梗死患者54例,均于发病3d内行MRI检查,在弥散加权成像(diffusion weighted imaging,DWI)、灌注加权成像(perfusion-weighted imaging,PWI)图像上采用半定量人工手动测量梗死体积并计算PWI-DWI不匹配(PWI-DWI mismatch,PDM);在SWI图像上对低密度血管影进行Albert卒中项目早期CT评分(Alberta Stroke Program Early CT score,ASPECTS),并依据ASPECTS评分将患者分为少血管影组15例(ASPECTS评分1~3分)、较多血管影组27例(ASPECTS评分4~6分)、大量血管影组12例(ASPECTS评分7~10分)。比较3组一般资料,DWI体积、PWI体积以及PDM;分析ASPECTS评分与PWI体积、PDM的相关性。结果大量血管影组年龄[(67.9±8.7)岁]较少血管影组[(57.8±15.6)岁]、多血管影组[(52.0±11.8)岁]大(P<0.05);3组性别比例,收缩压,合并心房颤动、糖尿病、高脂血症及吸烟比例差异无统计学意义(P>0.05);大量血管影组PWI体积[259.39(216.97,338.35)cm3]、PDM[208.44(110.58,252.99)cm3]大于少血管影组[91.21(66.34,202.40)cm3,24.99(0.91,91.25)cm3]、多血管影组[98.54(29.88,157.50)cm3,34.23(3.61,125.49)cm3](P<0.05),3组DWI体积[10.63(5.76,136.21)cm3,20.88(4.51,116.83)cm3,14.61(4.54,65.08)cm3]比较差异无统计学意义(P>0.05);Spearman秩相关检验结果显示,ASPECTS评分与PDM和PWI体积呈正相关(r=0.438,P=0.001;r=0.463,P=0.000)。结论 SWI的MHV可替代PWI预测急性脑梗死的缺血半暗带,SWI可作为预测急性脑梗死缺血半暗带的有用放射学工具指导临床治疗。
引用
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页码:57 / 61
页数:5
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