冠心病患者C反应蛋白变化的临床意义

被引：50

作者：

张善春

李琳

黄暄

齐惠英

郑刚

刘兆昶

机构：

[1] 天津市第三医院心内科,天津市第三医院,天津市第三医院,天津市第三医院,天津市第三医院,天津市第三医院

来源：

中国心血管杂志 | 2002年 / 01期

关键词：

C反应蛋白; 冠心病; 危险因素;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

目的　探讨 C反应蛋白 (CRP)与冠心病之间的关系。方法　冠心病组 (12 8例 )分为 3组 ,急性心肌梗死(AMI)组 34例 ,不稳定心绞痛 (U AP)组 49例 ,稳定性心绞痛 (SAP)组 45例。比较冠心病组各组间及与对照组(12 8例 )之间 CRP、白细胞 (WBC)、纤维蛋白原 (FIB)及血脂水平的差异。结果　冠心病组 CRP和 WBC水平高于对照组 (P分别为 0 .0 0 6和 0 .0 13) ,经调整性别、年龄、体重指数、吸烟史、高血压病及糖尿病史、血脂指标后 ,CRP和 WBC水平仍与冠心病患病率显著相关 ,OR(比数比 )分别为 1.6 83和 1.46 8(均 P<0 .0 5 )。 AMI组及 U AP组CRP水平与对照组相比有显著性差异 (P<0 .0 5 ,P<0 .0 0 1) ;UAP组与 SAP组相比 ,CRP水平也有显著性差异 (P<0 .0 5 ) ;而 SAP组与对照组相比 CRP水平则无明显差异 (P>0 .0 5 )。结论　 CRP是冠心病的独立危险因素。CRP升高提示冠心病患者病情不稳定

引用

页码：15 / 17

页数：3

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