中国冠心病抗栓治疗的探索与展望

被引：30

作者：

韩雅玲

机构：

[1] 沈阳军区总医院心内科

来源：

解放军医学杂志 | 2015年 / 40卷 / 04期

关键词：

冠心病; 血栓溶解疗法; 血管成形术;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

抗栓治疗是冠心病治疗的重要基石。实现冠心病抗栓治疗的优化,是心血管医师持续努力的目标之一。目前国内冠心病抗栓领域尚缺少高质量的随机对照临床研究,成为中国冠心病抗栓治疗亟待解决的重要问题。针对我国心血管抗栓治疗大数据研究的现状和东西方人群的差异,笔者所在中心于2012年进行了一些初步探索。本文在总结笔者多年临床研究经验的基础上,从冠心病抗栓治疗的热点、现状及策略探索等方面进行述评。

引用

页码：255 / 261

页数：7

共 13 条

[1] ST-segment elevation myocardial infarction in China from 2001 to 2011 (the China PEACE-Retrospective Acute Myocardial Infarction Study): a retrospective analysis of hospital data [J].

不详 .

LANCET, 2015, 385 (9966) :402-402

[2] Salvianolic acid B inhibits platelets as a P2Y12 antagonist and PDE inhibitor: Evidence from clinic to laboratory [J].

Liu, Lei ;

Li, Jian ;

Zhang, Yan ;

Zhang, Shenghui ;

Ye, Jianqin ;

Wen, Zhichao ;

Ding, Jianping ;

Kunapuli, Satya P. ;

Luo, Xinping ;

Ding, Zhongren .

THROMBOSIS RESEARCH, 2014, 134 (04) :866-876

[3]

A Randomized Comparison of Novel Biodegradable Polymer- and Durable Polymer–Coated Cobalt-Chromium Sirolimus-Eluting Stents.[J].Yaling Han;Bo Xu;Quanmin Jing;Shuzheng Lu;Lixia Yang;Kai Xu;Yi Li;Jing Li;Changdong Guan;Ajay J. Kirtane;Yuejin Yang.JACC: Cardiovascular Interventions.2014, 12

[4] Comparison of Dual Versus Triple Antiplatelet Therapy After Drug-Eluting Stent According to Stent Length (from the Pooled Analysis of DECLARE Trials) [J].

Lee, Seung-Whan ;

Lee, Jong-Young ;

Ahn, Jung-Min ;

Park, Duk-Woo ;

Han, Seungbong ;

Park, Yong Kyu ;

Lee, Woo Seok ;

Jang, Jeong Yoon ;

Kwon, Chang Hee ;

Park, Gyung-Min ;

Cho, Young-Rak ;

Kim, Won-Jang ;

Kang, Soo-Jin ;

Kim, Young-Hak ;

Lee, Cheol Whan ;

Kim, Jae-Joong ;

Park, Seong-Wook ;

Park, Seung-Jung .

AMERICAN JOURNAL OF CARDIOLOGY, 2013, 112 (11) :1738-1744

[5]

Differential Impact of Cilostazol on Restenosis According to Implanted Stent Type (from a Pooled Analysis of Three DECLARE Randomized Trials).[J].Seung-Whan Lee;Jung-Min Ahn;Seungbong Han;Gyung-Min Park;Young-Rak Cho;Woo-Seok Lee;Jeong-Yoon Jang;Chang-Hee Kwon;Jong-Young Lee;Won-Jang Kim;Soo-Jin Kang;Young-Hak Kim;Cheol-Whan Lee;Jae-Joong Kim;Seong-Wook Park;Seung-Jung Park.The American Journal of Cardiology.2013,

[6] Effect of the CYP2C19*2 and *3 genotypes, ABCB1 C3435T and PON1 Q192R alleles on the pharmacodynamics and adverse clinical events of clopidogrel in Chinese people after percutaneous coronary intervention [J].

Tang, Xiao-Fang ;

Wang, Jing ;

Zhang, Jia-Hui ;

Meng, Xian-Min ;

Xu, Bo ;

Qiao, Shu-Bin ;

Wu, Yong-Jian ;

Chen, Jue ;

Wu, Yuan ;

Chen, Ji-Lin ;

Gao, Run-Lin ;

Yuan, Jin-Qing ;

Yang, Yue-Jin .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2013, 69 (05) :1103-1112

[7]

Genetic determinants of high on-treatment platelet reactivity in clopidogrel treated Chinese patients.[J].Lanning Zhang;Yanming Chen;Ying Jin;Fei Qu;Jiayue Li;Cong Ma;Jie Yang;Bin Xu;Hongjuan Wang;Xiaoqi Li;Yang Li;Yuxiao Zhang;Caiyi Lu;Tong Yin.Thrombosis Research.2013,

[8] Triple antiplatelet therapy reduces ischemic events after drug-eluting stent implantation: Drug-Eluting stenting followed by Cilostazol treatment REduces Adverse Serious cardiac Events (DECREASE registry) [J].