炎症反应介导缺血性脑损伤的机制研究进展

被引：12

作者：

涂献坤

杨卫忠

石松生

机构：

[1] 福建医科大学附属协和医院神经外科

来源：

中华神经医学杂志 | 2011年 / 03期

关键词：

炎症反应; Toll样受体; 5-脂氧合酶; 细胞因子; 脑缺血;

D O I：

暂无

中图分类号：

R285.5 [中药实验药理];

学科分类号：

1008 ;

摘要：

<正>脑缺血诱导的缺血性脑损伤涉及一系列复杂的病理生理机制,包括兴奋性氨基酸中毒、离子稳态的失衡、梗死周边区去极化、血脑屏障的破坏、自由基损伤、炎症反应、神经元凋亡等,这些不同的病理生理机制在缺血脑组织中呈现时间、空间变化的动态过程。大量文献表明,炎症反应是脑缺

引用

页码：322 / 324

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