共 20 条
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Neurotoxity induces cleavage of p35 to p25 by calpain. Lee M S,Kwon Y T,Li M,et al. Nature . 2000
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The p35/cdk-5 kinase is a neuron-specific Rac effector that inhibits Pakl activity. Nikolic M,Chou M M,Lu W,et al. Nature . 1998
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The cdk-5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Nikolic M,Dudek H,Kwon Y T,et al. Genes and Development . 1996
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Tau protein kinase I convaents normal tau protein into A8-like component of paired helical filaments. Ishiguro K,Takamatsu M,Tomizawa K,et al. Journal of Biological Chemistry . 1992
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A Cdc2 related kinase PSSALRE/cdk-5 is homologous with the 30 kd subunit of tau protein kinase Ⅱ, a proline directed kinase associated with microtubules. Kobayashi S,Ishiguro K,Omori A,et al. FEBS Letters . 1993
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Involvement of aberrant glycosylation in phosphorylation of tau by cdk-5 and GSK-3β. Fei Liu,Khalid Iqbal,Inge Grundke-Iqabal,et al. FEBS Letters . 2002
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Conversion of p35 to p25 deregulates cdk-5 activity and promotes neurodegeneration. Patrick G N,Zukerberg L,Nikolic M,et al. Nature . 1999