氧化应激、氧化低密度脂蛋白和脂蛋白相关磷脂酶A2与动脉粥样硬化

被引：1

作者：

闫洁 ^{[1
]}

刘国荣 ^{[2
]}

李月春 ^{[2
]}

王宝军 ^{[2
]}

机构：

[1] 包头医学院

[2] 包头市中心医院神经科

来源：

国际脑血管病杂志 | 2011年 / 03期

关键词：

动脉粥样硬化; 氧化性应激; 活性氧; 脂质过氧化; 氧化低密度脂蛋白; 1-烷基-2-乙酰甘油磷酸胆碱酯酶; 危险因素;

D O I：

暂无

中图分类号：

R54 [心脏、血管（循环系）疾病];

学科分类号：

1002 ; 100201 ;

摘要：

氧化应激是动脉粥样硬化早期的一个重要危险因素,涉及线粒体损伤、自由基释放,脂质过氧化、磷脂酶激活以及炎症介质释放等多种病理生理学过程。越来越多的研究表明,氧化应激、氧化低密度脂蛋白和脂蛋白相关磷脂酶A2在动脉粥样硬化的发生和发展中起着重要的作用。因此,探讨其相互关系,有助于加深动脉粥样硬化的认识,并采取针对性预防。

引用

页码：237 / 240

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