直接PCI与溶栓后即刻和补救PCI对AMI患者近期心功能的影响

被引：1

作者：

李永旺

邓根群

曲鹏

吴君

张志刚

机构：

[1] 辽宁省大连市中心医院心内科

[2] 辽宁省辽阳市太子河区医院

[3] 辽宁省大连市中心医院心内科辽宁大连

[4] 辽宁大连

来源：

中国医师杂志 | 2004年 / 04期

关键词：

急性心肌梗死; 经皮冠状动脉介入治疗; 左室重构; 心功能;

D O I：

暂无

中图分类号：

R542.22 [];

学科分类号：

1002 ; 100201 ;

摘要：

目的　评价直接经皮冠状动脉介入治疗 (PCI)与小剂量rt -PA溶栓后即刻和补救PCI对急性心肌梗死 (AMI)患者的有效性和安全性 ,并观察其对近期左室重构及功能的影响。方法　对初次发病、发病 6h内且无溶栓禁忌症的AMI患者随机给予直接PCI或小剂量rt -PA溶栓加即刻和补救PCI治疗 ,于术后 3、3 0、90d行二维超声心动图检查并记录有关心脏事件。结果　共入选63例患者 ,随机分为直接PCI组 (对照组 ,A) 3 2例 ,溶栓加补救PCI组 (观察组 ,B) 3 1例。依据首次造影血流是否达TIMI 3级将所有病人再分为两组。术后 3、3 0、90d两组间左室收缩末期容积指数 (ESVI)、左室舒张末期容积指数 (EDSI)、左室射血分数 (EF)和室壁运动指数 (WMSI)均无显著差异 ( P >0 0 5 ) ;各组内 3 0d、90d与 3d比较均有显著差异 ;首次造影血流达TIMI 3级组与未达TIMI 3级组 3 0、90d各指标均显著改善。结论　直接PCI与小剂量rt -PA溶栓后即刻和补救PCI同样安全有效 ,改善左室功能并降低心脏事件的发生。

引用

页码：469 / 471

页数：3

共 7 条

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