围生期左脑损伤致言语认知障碍的评定及fMRI分析

被引:3
作者
郑修元 [1 ]
黄粉燕 [1 ]
燕铁斌 [1 ]
肖灵君 [1 ]
燕楠 [2 ]
林笑丰 [1 ]
梁志莹 [1 ]
机构
[1] 中山大学孙逸仙纪念医院
[2] 中国科学院深圳先进技术研究院
关键词
围生期; 左脑损伤; 言语认知障碍; 脑功能磁共振;
D O I
10.13261/j.issn.2096-0328.2015.04.001
中图分类号
R726.5 [小儿各生理系统外科学];
学科分类号
100202 ;
摘要
目的:探讨围生期左脑损伤对言语认知功能的影响。方法:应用3.0T MR仪对1例围生期左脑损伤患儿图片命名任务的BOLD f MRI扫描,应用Eprime 2.0任务程序设计软件进行编辑,使用模块设计模式(Block-design),静息相(不给予图像任务)与刺激相(给予图像任务)交替,患儿视图片时轻声对图片进行命名,观察脑区激活情况。通过韦氏儿童智力量表、体感诱发电位、运动诱发电位、脑电图、MR+MRA+DTI、艾森克个性问卷进行认知心理及神经功能评估。结果:患儿操作方面发展平衡(PVI=4.87),言语、总智力上发展不平衡(PVI=18.70、11.30),f MRI提示左脑病灶周围颞叶区脑组织激活。结论:围生期左脑损伤患儿言语表达障碍不明显,左脑损伤区周围的颞叶脑组织成为新的言语功能区。
引用
收藏
页码:1 / 4+30 +30
页数:5
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