同型半胱氨酸与老年冠心病患者内皮功能的关系

被引：4

作者：

陈哲

李春盛

张健

庞宝森

刘喜凤

机构：

[1] 首都医科大学附属北京朝阳医院综合科

[2] 首都医科大学附属北京朝阳医院综合科邮编

[3] 邮编

来源：

北京医学 | 2004年 / 01期

关键词：

同型半胱胺酸; 内皮细胞; 冠心病;

D O I：

10.15932/j.0253-9713.2004.01.006

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

目的　探讨血清同型半胱胺酸 (HCY)与老年冠心病患者内皮细胞损伤的关系。方法　对 76例行冠状动脉造影的患者检测血清中HCY、一氧化氮 (NO)、内皮素 - 1 (ET - 1 )、循环内皮细胞 (CEC)含量 ,以冠状动脉造影正常者做对照 ,进行t检验、线性相关分析。结果　冠心病组HCY、ET 1、CEC水平均明显高于对照组 (P <0 .0 1 ) ,NO水平显著低于对照组 (P <0 .0 1 ) ;从相关分析看 ,HCY与ET 1、CEC呈正相关 ,与NO/ET 1呈负相关(P <0 .0 5 )。结论　HCY与内皮细胞分泌NO、ET 1平衡失调有关。

引用

页码：14 / 17

页数：4

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