他汀类药物临床研究进展

被引:28
作者
孟锐
靳维华
机构
[1] 辽宁医学院校外培养基地北京航天中心医院
关键词
他汀类; PCI; 药物; 阿托伐他汀;
D O I
暂无
中图分类号
R972 [心血管系统药物];
学科分类号
1007 ;
摘要
<正>随着社会发展、人民生活水平提高,心脑血管疾病发病率逐年升高。血脂异常是导致动脉粥样硬化的主要因素之一,与冠心病、高血压、脑卒中等疾病密切相关,因此,调脂药物已广泛应用于临床。目前应用最多的调脂药是羟甲基戊二酸单酰辅酶A(HMG-CoA)还原酶抑制剂(他汀)。他汀类药物拥有共同的药效基团,即二羟基庚酸基团,它对抑制HMG-CoA还原酶活性是必需的。
引用
收藏
页码:130 / 132
页数:3
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