同型半胱氨酸与轻度血管性认知障碍

被引：11

作者：

刘险峰

张国华

机构：

[1] 河北医科大学第二医院神经内科

来源：

国际脑血管病杂志 | 2007年 / 15卷 / 10期

关键词：

同型半胱氨酸; 血管性认知障碍; 血管性痴呆; 白质疏松症;

D O I：

暂无

中图分类号：

R749.13 [];

学科分类号：

100205 ;

摘要：

高同型半胱氨酸血症是心脑血管病的一个重要独立危险因素。近年来的研究表明,高同型半胱氨酸血症也是血管性痴呆和Alzheimer病的独立危险因素。轻度血管性认知障碍是血管性痴呆的前期阶段。同型半胱氨酸可能主要通过损伤血管壁结构及其功能而与轻度血管性认知障碍具有相关性。

引用

页码：762 / 766

页数：5

共 13 条

[1] 血浆同型半胱氨酸水平升高与动脉粥样硬化(英文) [J].

杨帆 ;

谭红梅 ;

王虹 .

生理学报, 2005, (02) :103-114

[2]

Leukoaraiosis and Ischemia: Beyond the Myth[J] . David G. Munoz.Stroke . 2006 (6)

[3]

Total Homocysteine Is Associated With White Matter Hyperintensity Volume: The Northern Manhattan Study[J] . Clinton B. Wright,Myunghee C. Paik,Truman R. Brown,Sally P. Stabler,Robert H. Allen,Ralph L. Sacco,Charles DeCarli.Stroke . 2005 (6)

[4] Homocysteine and cognitive function in a population-based study of older adults [J].

Schafer, JH ;

Glass, TA ;

Bolla, KI ;

Mintz, M ;

Jedlicka, AE ;

Schwartz, BS .

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2005, 53 (03) :381-388

[5]

Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe[J] . T den Heijer,L J. Launer,N D. Prins,E J. van Dijk,S E. Vermeer,A Hofman,P J. Koudstaal,M M.B. Breteler.Neurology . 2005 (2)

[6]

Homocysteine, cerebrovascular disease and brain atrophy[J] . Perminder Sachdev.Journal of the Neurological Sciences . 2004 (1)

[7] Homocysteine and B vitamins relate to brain volume and white-matter changes in geriatric patients with psychiatric disorders [J].

Scott, TM ;

Tucker, KL ;

Bbadelia, A ;

Benjamin, B ;

Patz, S ;

Bbadelia, R ;

Liebson, E ;

Price, LL ;

Griffith, J ;

Rosenberg, I ;

Folstein, MF .

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2004, 12 (06) :631-638

[8] Homocysteine attenuates hemodynamic responses to nitric oxide in vivo [J].

Fu, WY ;

Dudman, NPB ;

Perry, MA ;

Wang, XL .

ATHEROSCLEROSIS, 2002, 161 (01) :169-176

[9]

Homocysteine, silent brain infarcts, and white matter lesions: The Rotterdam scan study[J] . Sarah E.Vermeer,Ewoud J.Van Dijk,Peter J.Koudstaal,MatthijsOudkerk,AlbertHofman,RobertClarke,Monique M.B.Breteler.Ann Neurol. . 2002 (3)

[10] Hippocampal and cortical atrophy predict dementia in subcortical ischemic vascular disease [J].

Fein, G ;

Di Sclafani, V ;

Tanabe, J ;

Cardenas, V ;

Weiner, MW ;

Jagust, WJ ;

Reed, BR ;

Norman, D ;

Schuff, N ;

Kusdra, L ;

Greenfield, T ;

Chui, H .

NEUROLOGY, 2000, 55 (11) :1626-1635

← 1 2 →