脑卒中高危人群早期颈动脉粥样硬化与血同型半胱氨酸水平的关系

被引:4
作者
李学慧
宋斌
夏仲芳
李晓波
张真稳
张桁忠
机构
[1] 苏北人民医院
关键词
脑卒中; 高危人群; 颈动脉粥样硬化; 同型半胱氨酸;
D O I
10.13668/j.issn.1006-9070.2018.01.12
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
探讨社区脑卒中高危人群早期颈动脉粥样硬化与血浆同型半胱氨酸(HCY)之间的关系。方法2013年10月—2014年4月在扬州地区选取≥40岁常驻社区居民为调查对象,通过危险因素评估确定脑卒中高危人群,进行血液生化检测及颈动脉超声检查,并对早期颈动脉粥样硬化的相关危险因素进行分析。结果纳入研究的脑卒中高危人群994人,血HCY的中位数9.0μmol/L,高HCY率为15.3%,早期颈动脉粥样硬化患病率为48.5%;颈动脉正常组和异常组高HCY率分别是9.9%、21.0%,组间差异有统计学意义(P<0.05);在校正了所有的混杂因素后,高HCY组发生早期颈动脉粥样硬化的风险是HCY正常组的2.1倍。结论社区脑卒中高危人群中血HCY升高是发生早期颈动脉粥样硬化的独立危险因素。
引用
收藏
页码:38 / 41
页数:4
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