血管内皮祖细胞治疗缺血性心脏病的研究进展

被引：3

作者：

陈闽荔

张金莲

吕建国

机构：

[1] 天津市胸科医院心内科

来源：

医学综述 | 2009年 / 15卷 / 18期

关键词：

内皮祖细胞; 缺血性心脏病; 治疗; 细胞移植;

D O I：

暂无

中图分类号：

R541 [心脏疾病];

学科分类号：

1002 ; 100201 ;

摘要：

内皮祖细胞是内皮细胞的前体细胞,是一类能够迁移、增殖,并分化为成熟血管内皮细胞的前体细胞,属于干细胞群体,参与人胚胎血管生成及出生后血管新生和内皮损伤后的修复过程,还可在一定条件下分化为心肌细胞。近年来的研究表明其与冠心病发生、发展及治疗的关系密切,为冠心病治疗提供了新思路。本文就内皮祖细胞的生物学特性及其在缺血性心脏病中的临床研究现状予以综述。

引用

页码：2753 / 2756

页数：4

共 8 条

[1]

Endothelial Progenitor Cell Capture by Stents Coated With Antibody Against CD34[J] . Jiro Aoki,Patrick W. Serruys,Heleen van Beusekom,Andrew T.L. Ong,Eugene P. McFadden,Georgios Sianos,Willem J. van der Giessen,Evelyn Regar,Pim J. de Feyter,H. Richard Davis,Stephen Rowland,Michael J.B. Kutryk.Journal of the American College of Cardiology . 2005 (10)

[2] Effects of Ginkgo biloba extract on number and activity of endothelial progenitor cells from peripheral blood [J].

Chen, JZ ;

Wang, XX ;

Zhu, JH ;

Shang, YP ;

Guo, XG ;

Sun, J .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2004, 43 (03) :347-352

[3]

Infarct Remodeling After Intracoronary Progenitor Cell Treatment in Patients With Acute Myocardial Infarction （TOPCARE-AMI）: Mechanistic Insights From Serial Contrast-Enhanced Magnetic Resonance Imaging[J] . Circulation: Journal of the American Heart Association . 2003 (18)

[4]

Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease[J] . Shmuel Fuchs,Lowell F Satler,Ran Kornowski,Petros Okubagzi,Giora Weisz,Richard Baffour,Ron Waksman,Neil J Weissman,Manuel Cerqueira,Martin B Leon,Stephen E Epstein.Journal of the American College of Cardiology . 2003 (10)

[5] Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling [J].

Aicher, A ;

Brenner, W ;

Zuhayra, M ;

Badorff, C ;

Massoudi, S ;

Assmus, B ;

Eckey, T ;

Henze, E ;

Zeiher, AM ;

Dimmeler, S .

CIRCULATION, 2003, 107 (16) :2134-2139

[6] Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemia [J].

Kawamoto, A ;

Tkebuchava, T ;

Yamaguchi, JI ;

Nishimura, H ;

Yoon, YS ;

Milliken, C ;

Uchida, S ;

Masuo, O ;

Iwaguro, H ;

Ma, H ;

Hanley, A ;

Silver, M ;

Kearney, M ;

Losordo, DW ;

Isner, JM ;

Asahara, T .

CIRCULATION, 2003, 107 (03) :461-468

[7] Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction -: (TOPCARE-AMI) [J].

Assmus, B ;

Schächinger, V ;

Teupe, C ;

Britten, M ;

Lehmann, R ;

Döbert, N ;

Grünwald, F ;

Aicher, A ;

Urbich, C ;

Martin, H ;

Hoelzer, D ;

Dimmeler, S ;

Zeiher, AM .

CIRCULATION, 2002, 106 (24) :3009-3017

[8]

Hematopoiesis and angiogenesis. Suda T, Takakura N, Oike Y. International Journal of Hematology . 2000

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