肱动脉内皮依赖性舒张功能与脑梗死危险因素高血压、糖尿病及高脂血症的相关研究

被引：5

作者：

陈洪汉 ^{[1
]}

黎红华 ^{[1
]}

向慧娟 ^{[2
]}

武强 ^{[1
]}

杨梅 ^{[1
]}

徐志鹏 ^{[1
]}

机构：

[1] 中国人民解放军广州军区武汉总医院神经内科

[2] 中国人民解放军广州军区武汉总医院超声影像科

来源：

脑与神经疾病杂志 | 2012年 / 20卷 / 05期

关键词：

脑梗死; 肱动脉内皮依赖性舒张功能; 高血压; 糖尿病; 高脂血症;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

1002 ;

摘要：

目的探讨肱动脉内皮依赖性舒张功能(FMD)与脑梗死危险因素中高血压、糖尿病及高脂血症的相关性。方法选取急性脑梗死患者40例,健康对照组11例,将急性脑梗死患者中单一危险因素者归列为单危险因素脑梗死组,2～3个危险因素者归列为多危险因素脑梗死组,均行肱动脉内皮功能检测。组间比较采用t检验。将FMD作为因变量,高血压、糖尿病及高脂血症作为自变量行多元线性回归分析。结果脑梗死组FMD较对照组显著降低,多危险因素脑梗死组FMD较单危险因素脑梗死组显著降低。高血压和糖尿病与FMD存在线性回归关系。结论高血压、糖尿病及高脂血症等脑梗死危险因素越多,FMD降低越显著,其中以高血压病与FMD的改变关系最密切,其次为糖尿病。

引用

页码：321 / 323

页数：3

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