VEGF和内皮抑素对血管生成作用的研究进展

被引：16

作者：

王韧

侯立军

机构：

[1] 第二军医大学长征医院神经外科

来源：

重庆医学 | 2011年 / 40卷 / 25期

关键词：

血管内皮生长因子; 内皮抑素; 血管生成;

D O I：

暂无

中图分类号：

R651.15 [];

学科分类号：

1002 ; 100210 ;

摘要：

<正>脑组织缺血、缺氧是创伤性脑损伤(traumatic brain injury,TBI)最常见的继发性损害,直接影响患者的预后。血管再生是创伤及缺血组织的病理生理反应,由血管再生因子和血管再生抑制因子共同参与调控。血管内皮生长因子(vascular endothelial growth factor,VEGF)是一种多功能糖蛋白,是主要的促血管生成因子。迄今发现,内皮抑素(endostatin,ES)是一种特异性作用最强的血管形成抑制剂。现将VEGF和ES对血管生成的作用研究进展作一综述。

引用

页码：2582 / 2585

页数：4

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