中国人非瓣膜性心房颤动脑卒中危险因素的病例-对照研究

被引：360

作者：

胡大一

孙艺红

周自强

李奎宝

倪永斌

杨光

孙淑红

李蕾

机构：

[1] 北京大学人民医院心内科,北京大学人民医院心内科,首都医科大学同仁医院心内科,北京大学人民医院心内科,北京大学人民医院心内科,首都医科大学同仁医院心内科,北京大学人民医院心内科,北京大学人民医院心内科,,,,,

来源：

中华内科杂志 | 2003年 / 03期

关键词：

心房颤动; 脑血管意外; 危险因素;

D O I：

暂无

中图分类号：

R541.75 [];

学科分类号：

1002 ; 100201 ;

摘要：

目的　本研究通过回顾性病例对照研究分析中国人心房颤动 (房颤 )脑卒中的危险因素。方法　在全国 1 8家医院共登记房颤患者 4 51 1例 ,其中风湿瓣膜性房颤 1 0 86例 ,非瓣膜性房颤 342 5例。通过比较房颤合并脑卒中与房颤无脑卒中患者 ,筛选房颤发生脑卒中的危险因素。结果　中国人房颤脑卒中的患病率 2 4 81 % ,房颤合并脑卒中组年龄明显高于对照组 (P <0 0 0 1 ) ,且患病率随年龄增长而明显增加。多因素Logistic分析显示 :年龄≥ 75岁 (OR 1 76 ,95 %CI 1 0 8～ 2 98) ,高血压病史 (OR 1 52 ;95 %CI 1 2 8～ 1 80 ) ,糖尿病史 (OR 1 39,95 %CI 1 1 1～ 1 76) ,动脉收缩压升高(OR 1 71 ,95 %CI1 2 1～ 2 2 8) ,左房血栓 (OR 2 77,95 %CI 1 2 5～ 6 1 3)是脑卒中的独立危险因素。结论　中国人非瓣膜性房颤脑卒中的独立危险因素为年龄、高血压病史、糖尿病史、左房血栓、动脉收缩压升高 ,上述因素对决定房颤患者的抗栓治疗策略具有重要意义

引用

页码：16 / 20

页数：5

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