S100蛋白功能和结构研究进展

被引：4

作者：

李国明 ^{[1
]}

戴克胜 ^{[1
]}

李天才 ^{[2
]}

机构：

[1] 北京航空航天大学生物与医学工程学院

[2] 中国科学院西北高原生物研究所

来源：

生物技术通报 | 2011年 / 06期

关键词：

S100蛋白; 钙离子; 功能; 结构;

D O I：

10.13560/j.cnki.biotech.bull.1985.2011.06.026

中图分类号：

Q51 [蛋白质];

学科分类号：

071010 ; 081704 ;

摘要：

S100蛋白作为Ca2+调节蛋白广泛存在于各种脊椎动物中。它们参与调控蛋白磷酸化、酶活性、细胞增殖分化、细胞骨架组成的动力学、膜结构组成、维持细胞间Ca2+浓度的恒定、参与炎症反应,以及保护细胞免受氧化损伤等。对S100蛋白的一般特征、细胞内外的功能及结构的研究进展等方面做了比较全面的阐述。部分S100蛋白三维结构的解析为进一步探讨其功能提供了直观的信息。

引用

页码：12 / 16

页数：5

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