脂联素与冠心病及其危险因素关系的研究进展

被引：7

作者：

徐昶

周强

马业新

机构：

[1] 华中科技大学同济医学院附属同济医院心内科

来源：

中国动脉硬化杂志 | 2008年 / 02期

关键词：

内科学; 脂联素; 冠心病; 血脂异常; 胰岛素抵抗; 糖尿病; 高血压;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

脂联素是脂肪细胞分泌的脂肪因子之一,与代谢综合征的各组分关系密切,成为近来研究的热点。本文就脂联素与冠心病及其危险因素关系的最新研究进展进行综述。

引用

页码：158 / 160

页数：3

共 8 条

[1] 不同类型冠心病患者血清脂联素水平及冠心病危险因素的变化 [J].

刘叶 ;

于晓玲 .

中国心血管病研究杂志, 2006, (04) :287-289

[2] 低脂联素血症是冠状动脉粥样硬化严重程度的重要标志 [J].

刘岩 ;

邹大进 ;

李慧 ;

陈月 ;

丁继军 ;

郑兴 ;

郭鹏飞 .

中华内分泌代谢杂志, 2005, (01) :9-12

[3] Effect of adiponectin on carotid arterial stiffness in type 2 diabetic patients treated with pioglitazone and metformin [J].

Araki, Takahiro ;

Emoto, Masanori ;

Teramura, Megumi ;

Yokoyama, Hisayo ;

Mori, Katsuhito ;

Hatsuda, Sawako ;

Maeno, Takaaki ;

Shinohara, Kayo ;

Koyama, Hidenori ;

Shoji, Tetsuo ;

Inaba, Masaaki ;

Nishizawa, Yoshiki .

METABOLISM-CLINICAL AND EXPERIMENTAL, 2006, 55 (08) :996-1001

[4]

Low adipocyte-derived plasma protein adiponectin concentrations are associated with the metabolic syndrome and small dense low-density lipoprotein particles: atherosclerosis and insulin resistance study[J] . Metabolism . 2003 (12)

[5] Adiponectin gene expression is inhibited by β-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes [J].

Fasshauer, M ;

Klein, J ;

Neumann, S ;

Eszlinger, M ;

Paschke, R .

FEBS LETTERS, 2001, 507 (02) :142-146

[6]

Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity[J] . Yukio Arita,Shinji Kihara,Noriyuki Ouchi,Masahiko Takahashi,Kazuhisa Maeda,Jun-ichiro Miyagawa,Kikuko Hotta,Iichiro Shimomura,Tadashi Nakamura,Koji Miyaoka,Hiroshi Kuriyama,Makoto Nishida,Shizuya Yamashita,Kosaku Okubo,Kenji Matsubara,Masahiro Muraguchi,Yasuichi Ohmoto,Tohru Funahashi,Yuji Matsuzawa.Biochemical and Biophysical Research Communications . 1999 (1)

[7]

cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 ( A di p ose M ost Abundant Gene Transcript 1)[J] . Kazuhisa Maeda,Kousaku Okubo,Iichiro Shimomura,Tohru Funahashi,Yuji Matsuzawa,Kenichi Matsubara.Biochemical and Biophysical Research Communications . 1996 (2)

[8]

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK-and COX-2-dependent mechanisms .2 ShibataR,SatoK,PimentelDR,TakemuraY,KmaraS,Ohashi K,Funahashi T,Ouchi N,W alsh K. Nat Med . 2005

← 1 →