养血清脑颗粒对老年脑梗死后抑郁患者血清胱抑素C及认知功能的影响

被引：14

作者：

王晓萍 ^{[1
]}

彭军 ^{[1
]}

姜丹 ^{[1
]}

黄丹 ^{[1
]}

刘孙琴 ^{[2
]}

机构：

[1] 武汉科技大学附属天佑医院神经内科

[2] 武汉科技大学附属天佑医院检验科

来源：

现代生物医学进展 | 2017年 / 17卷 / 08期

关键词：

养血清脑颗粒; 脑梗死; 抑郁; 血清胱抑素C; 认知功能;

D O I：

10.13241/j.cnki.pmb.2017.08.018

中图分类号：

R743.33 [脑栓塞]; R749.4 [情感性精神病];

学科分类号：

1002 ; 100205 ;

摘要：

目的:探究养血清脑颗粒对老年脑梗死后抑郁患者血清胱抑素C水平的影响及认知功能水平的影响。方法:选取2015年6月到2016年6月我院神经内科收治的老年脑梗死后抑郁患者74例,根据随机数字对照表分为对照组与试验组,各37例。对照组采用口服盐酸帕罗西汀治疗,试验组联合给予养血清脑颗粒治疗,4周为一个疗程,共治疗一个疗程。比较两组患者临床疗效、血清胱抑素C水平及认知功能水平。结果:治疗结束后,与对照组相比,试验组临床总有效率较高(P<0.05),治疗后两组血清胱抑素C水平较治疗前降低(P<0.05),MMSE评分较治疗前升高(P<0.05);与对照组相比,血清胱抑素C水平较低(P<0.05),MMSE评分较高(P<0.05)。结论:养血清脑颗粒治疗老年脑梗死后抑郁患者临床疗效显著,认知功能明显改善,推测其与血清胱抑素C水平降低有关。

引用

收藏

页码：1477 / 1479+1573 +1573

页数：4

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