急性脑梗死患者合并脑微出血的心脑血管事件发生的研究

被引：13

作者：

李晓晴

毕齐

王力

王力峰

机构：

[1] 首都医科大学附属北京安贞医院神经内科

来源：

中华老年心脑血管病杂志 | 2012年 / 14卷 / 11期

关键词：

脑梗死; 脑出血; 脑缺血; 磁共振成像; 抗凝药; 血小板聚集抑制剂;

D O I：

暂无

中图分类号：

R743.33 [脑栓塞];

学科分类号：

1002 ;

摘要：

目的研究急性脑梗死合并脑微出血（CMB）患者后期心脑血管事件的发生率和危险因素。方法将109例急性脑梗死患者分为CMB组38例和无CMB组71例,对其进行前瞻性研究,给予梯度回波T2*WI或磁敏感加权成像,并对患者的临床资料和影像学特点进行分析。平均随访（9.5±3.7）个月。结果与无CMB组比较,CMB组脑梗死和脑出血两者兼有,单纯脑出血比例明显升高（7.9%vs 1.4%,P<0.05;10.5%vs 0,P<0.01）。CMB组共检出CMB 153个。在随访中,1 6例患者再发脑卒中,包括11例脑梗死,5例脑出血。5例脑出血患者中有3例服用阿司匹林,2例接受抗凝治疗。CMB组有2例脑出血患者的出血部位与CMB部位相同。结论 CMB是脑微小血管病变特征之一;是急性缺血性脑血管病患者后期发生脑出血的危险因素之一;CMB对脑卒中患者长期服用阿司匹林或者抗凝治疗具有重要意义。

引用

页码：1124 / 1126

页数：3

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