Objective:To observe the therapeutic effect of acupuncture on post-stroke anxiety neurosis(PSAN).Methods:34 patients in the treatment group received acupuncture treatment.Points such as Baihui(GV 20),Shenting(GV 24),Yintang(EX-HN 3),Shuigou(GV 26),Hegu(LI 4),Taichong(LR 3),Shenmen(HT 7) and Neiguan(PC 6) were punctured and supplemented by electroacupuncture.33 patients in the control group orally took Alprazolam.Hamilton Anxiety Scale(HAMA) was used to evaluate the severity and relief of anxiety.Results:Anxiety symptoms of the patients in the treatment group were obviously relieved with a total effective rate of 82.35%,and no remarkable difference was found as compared with that of the control group(P>0.05).Conclusions:Acupuncture is a safe,effective and important method for treating PSAN.