女性冠心病患者的危险因素分析及与冠脉病变严重程度的关系

被引：3

作者：

姚峰 ^{[1
]}

曹繁华 ^{[2
]}

尹俊 ^{[1
]}

徐智虎 ^{[1
]}

朱磊 ^{[1
]}

机构：

[1] 湖北省武汉市第六医院心血管内科

[2] 湖北省宜昌市中医医院肾内科

来源：

现代生物医学进展 | 2015年 / 15卷 / 19期

关键词：

冠心病; 危险因素; 冠脉病变; 女性;

D O I：

10.13241/j.cnki.pmb.2015.19.037

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

目的:了解女性冠心病患者的危险因素及与冠脉病变严重程度的关系。方法:随机选取本院2012年至2014年心血管科住院治疗的疑似冠心病女性患者150例,经冠脉造影确诊冠心病患者105例,非冠心病患者45例。对患者的临床资料和冠脉病变严重程度进行单因素和多因素分析。结果:冠心病患者高血压与糖尿病百分比、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C)及纤维蛋白原水平均高于非冠心病患者,而高密度脂蛋白(HDL-C)和血红蛋白水平均低于非冠心病患者(P<0.05);年龄、高血压与糖尿病百分比、血脂上升百分比(高TC、高TG、低HDL-C、高LDL-C)、高尿酸百分比和纤维蛋白原水平均随冠状动脉病变支数及Gensini积分的增加而增加(P<0.05);多因素分析发现女性冠心病的影响因素分别为高LDL-C、糖尿病、低HDL-C、TG和高血压,其中高LDL-C的影响最为显著(P<0.05)。结论:高血压、糖尿病史、血脂水平为女性冠心病的影响因素,其中高LDL-C的影响最显著,各影响因素均与冠脉病变程度紧密相关。

引用

页码：3736 / 3739

页数：4

共 11 条

[1] Coronary artery disease in women:From the yentl syndrome to contemporary treatment [J].

Sofia Vaina ;

Anastasios Milkas ;

Christina Crysohoou ;

Christodoulos Stefanadis .

World Journal of Cardiology, 2015, 7 (01) :10-18

[2] 康复护理干预对冠心病冠状动脉介入治疗患者生活质量的影响 [J].

何翠芳 .

辽宁医学院学报, 2013, 34 (01) :91-93

[3]

Impact of age on mean platelet volume and its relationship with coronary artery disease: A single-centre cohort study[J] . Monica Verdoia,Alon Schaffer,Lucia Barbieri,Giorgio Bellomo,Paolo Marino,Fabiola Sinigaglia,Harry Suryapranata,Giuseppe De Luca. Experimental Gerontology . 2015

[4]

Relation of ABO blood groups to the severity of coronary atherosclerosis: An Gensini score assessment[J] . Ping Gong,Song-Hui Luo,Xiao-Lin Li,Yuan-Lin Guo,Cheng-Gang Zhu,Rui-Xia Xu,Sha Li,Qian Dong,Geng Liu,Juan Chen,Rui-Xiang Zeng,Jian-Jun Li. Atherosclerosis . 2014 (2)

[5]

Genetics of coronary artery disease – A clinician perspective[J] . Manda V. Sasidhar,Satyajit Reddy,Ashutosh Naik,Sudhir Naik. Indian Heart Journal . 2014

[6]

Healthy Lifestyle and Decreasing Risk of Heart Failure in Women[J] . Golareh Agha,Eric B. Loucks,Lesley F. Tinker,Molly E. Waring,Dominique S. Michaud,Randi E. Foraker,Wenjun Li,Lisa W. Martin,Philip Greenland,JoAnn E. Manson,Charles B. Eaton. Journal of the American College of Cardiology . 2014 (17)

[7]

Effects of FX06 In Vitro on Platelet, Coagulation, and Fibrinolytic Biomarkers in Volunteers and Patients With Documented Coronary Artery Disease[J] . Jonas Hallén,Dan Atar,Victor Serebruany. American Journal of Therapeutics . 2014 (2)

[8] Statin treatment patterns and clinical profile of patients with risk factors for coronary heart disease defined by National Cholesterol Education Program Adult Treatment Panel III [J].

Kern, David M. ;

Balu, Sanjeev ;

Tunceli, Ozgur ;

Anzalone, Deborah .

CURRENT MEDICAL RESEARCH AND OPINION, 2014, 30 (12) :2443-2451

[9] Prevalence and pattern of lipid disorders in Saudi patients with angiographically documented coronary artery disease [J].

Al-Shehri, Abdullah M. .

JOURNAL OF FAMILY AND COMMUNITY MEDICINE, 2014, 21 (03) :166-169

[10] Exercise training enhances multiple mechanisms of relaxation in coronary arteries from ischemic hearts [J].

Deer, Rachel R. ;

Heaps, Cristine L. .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2013, 305 (09) :H1321-H1331

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