超声检测颈动脉粥样硬化与冠心病心脏事件的关系

被引:5
作者
徐欣
杨志健
郑义通
徐默玲
杨承健
雍永宏
机构
[1] 无锡市第二人民医院心血管内科
[2] 江苏省人民医院心血管内科
[3] 江苏省人民医院心血管内科 江苏无锡
[4] 江苏南京
[5] 江苏无锡
关键词
动脉粥样硬化,冠状动脉; 颈动脉; 超声检查; 心脏事件;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
1002 ; 100201 ;
摘要
目的 探讨颈动脉粥样硬化与冠状动脉粥样硬化的相关性 ,评价超声检测颈动脉粥样硬化对冠心病心脏事件预测的可能性。方法 将 2 33例疑是冠心病和心肌梗死患者行选择性冠状动脉造影及颈动脉超声检查 ,同时随访其心脏事件发生情况。分析颈动脉内中膜厚度 (IMT)及斑块与冠心病、冠心病危险因素及冠心病心脏事件发生情况的相关性。结果  2 33例患者有 14 0例颈动脉超声阳性即IMT≥ 0 .8mm(6 0 .1% ) ,颈动脉超声阳性与性别、年龄、体重指数、糖尿病、高血压、痛风、吸烟、家族史、不稳定型心绞痛、心肌梗死、经皮冠状动脉腔内成形术、冠状动脉搭桥术、冠状动脉造影二支病变、冠状动脉造影三支病变、超声心动图异常、运动平板试验异常、异常Q波、ST段改变呈正相关 (P <0 .0 5 ) ;2 33例随访率为 94 .8% ,有 4 6例患者发生 4 8件心脏事件 ,其发生与体重指数、不稳定型心绞痛、冠状动脉造影阳性、冠状动脉造影二支病变、冠状动脉造影三支病变、颈动脉超声阳性、颈动脉斑块呈正相关 ,且关系密切 (P <0 .0 5 ) ;多因素非条件Logistic回归分析排除混杂因素影响 ,显示颈动脉超声阳性与阴性患者的心脏事件差别有统计学意义 (P <0 .0 5 )。结论 颈动脉粥样硬化与冠心病及冠心病危险因素之间关系密切 ,颈动脉超声
引用
收藏
页码:844 / 847
页数:4
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