老年冠心病患者合并非酒精性脂肪性肝病的危险因素分析

被引:7
作者
李庆祥 [1 ,2 ]
李艳芳 [1 ,2 ]
王春梅 [1 ,2 ]
高玉龙 [1 ,2 ]
朱小玲 [1 ,2 ]
机构
[1] 首都医科大学附属北京安贞医院心肺抢救中心病房
[2] 北京市心肺血管疾病研究所
关键词
冠心病; 脂肪肝; 糖尿病; 高血压; 危险因素;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
1002 ; 100201 ;
摘要
目的探讨老年冠心病患者合并非酒精性脂肪性肝病(NAFLD)的患病率和危险因素。方法入选冠状动脉造影诊断为冠心病的老年患者359例,NAFLD组172例,非NAFLD组187例,住院期间经腹部超声检查和采集病史,观察2组患病率、肝脏酶学异常比例及其与冠状动脉病变程度的关系。结果 NAFLD组糖尿病、丙氨酸转氨酶、天冬氨酸转氨酶水平明显高于非NAFLD组,差异有统计学意义(P<0.05,P<0.01)。NAFLD与冠状动脉病变严重程度呈正相关(χ2=16.182,P<0.01)。NAFLD组患者斑块检出率、斑块数目明显高于非NAFLD组,差异有统计学意义[89.7%vs 78.3%,(2.27±1.20)个vs(1.81±1.32)个,P<0.05]。多因素logistic回归分析显示,糖尿病和冠状动脉多支病变(或左主干病变)与NAFLD的发生相关。结论老年冠心病患者NAFLD的患病率随着冠状动脉病变程度加重而增加。
引用
收藏
页码:369 / 372
页数:4
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