阿尔茨海默病中的钙紊乱机制研究进展

被引：8

作者：

陈艳杏

孙圣刚

机构：

[1] 华中科技大学同济医学院附属协和医院神经内科

来源：

国际神经病学神经外科学杂志 | 2009年 / 36卷 / 05期

关键词：

阿尔茨海默病; 钙; 钙紊乱; 钙稳态;

D O I：

10.16636/j.cnki.jinn.2009.05.019

中图分类号：

R749.16 [];

学科分类号：

100203 ;

摘要：

阿尔茨海默病是最常见的神经变性病,也是老年痴呆最常见的形式,其发病机制已得到广泛而深入的研究,并为临床药物治疗提供了理论基础。阿尔茨海默病中的钙紊乱机制很早就已经提出,并被后来的研究不断论证和补充。近年来对钙调节机制在阿尔茨海默病发病中的作用研究又取得了很大的进展,包括家族性痴呆变异基因引起的钙紊乱机制的研究,新的基因多态性的发现等,这些研究结果为进一步了解阿尔茨海默病的发病机制提供了新的视点,将为临床药物治疗提供新的靶点。

引用

页码：441 / 444

页数：4

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