超选择动脉内溶栓联合支架成形术治疗急性脑梗死

被引:5
作者
蔡学礼 [1 ]
邱伟文 [1 ]
程伟进 [1 ]
黄跃金 [1 ]
彭潇 [1 ]
焦力群 [2 ]
机构
[1] 温州医学院附属第五医院神经内科(浙江省丽水市中心医院)
[2] 首都医科大学宣武医院介入中心
关键词
血栓溶解疗法/方法; 输注,动脉内; 血管成形术; 支架; 脑梗死/治疗; 急性病; 回顾性研究;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
1002 ;
摘要
目的探讨超选择动脉内溶栓联合支架成形术治疗急性脑梗死的临床疗效。方法回顾性分析52例急性脑梗死动脉溶栓患者的临床资料,年龄48~72(60.2±7.9)岁,患者发病时间3.5~10.5(4.6±2.9)h。将微导管超选择送至血管闭塞部位,注入组织纤溶酶原激活物(r-tPA)行动脉内溶栓。血管无明显再通或存在明显狭窄的患者在溶栓后采用支架血管内成形术。结果治疗后完全再通37例,部分再通15例。入院时NIHSS评分为9~25(16.3±3.4)分。溶栓24 h后NIHSS评分为1~25(10.4±4.1)分,差异有统计学意义(P<0.01)。溶栓3个月后改良RANKIN量表(MRS)评分≤2分30例,MRS评分3分10例,MRS评分4分6例,MRS评分5分3例,死亡3例。结论超选择动脉内接溶栓治疗急性脑梗死有较好效果,合并严重动脉狭窄患者可行球囊扩张支架植入术,再通不理想未明确狭窄情况患者也可考虑行球囊扩张支架植入术。
引用
收藏
页码:1104 / 1106
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