远程缺血预适应对冠心病支架治疗患者的心肌保护作用

被引：9

作者：

雒生杰 ^{[1
]}

周玉杰 ^{[2
]}

贾德安 ^{[2
]}

葛海龙 ^{[2
]}

杨士伟 ^{[2
]}

机构：

[1] 北京市朝阳区双桥医院心内科

[2] 首都医科大学附属安贞医院心内科

来源：

中国循证心血管医学杂志 | 2016年 / 8卷 / 07期

关键词：

远程缺血预适应; 经皮冠状动脉介入治疗; 冠心病; 支架; 肌钙蛋白;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

目的探讨远程缺血预适应对冠状动脉支架治疗患者的心肌保护作用。方法将148例行择期冠状动脉支架术的非糖尿病的冠心病患者随机分为两组:远程缺血预适应组75例,术前2 h内进行预适应处理;未行预适应处理对照组73例。观察术后肌钙蛋白I水平和4a型心肌梗死(支架术相关心肌梗死)发生率。结果远程缺血预适应组术后16 h超敏肌钙蛋白I中位数值显著低于对照组(0.11ng/ml vs.0.27ng/ml,P<0.05),4a型心肌梗死发生率显著低于对照组(39%vs.56%,P<0.05)。结论远程缺血预适应可降低择期PCI术后肌钙蛋白I水平及4a型心肌梗死发生率。

引用

页码：808 / 811

页数：4

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